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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPX2
All Species:
17.58
Human Site:
T59
Identified Species:
38.67
UniProt:
Q9ULW0
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULW0
NP_036244.2
747
85653
T59
G
G
L
F
Q
G
K
T
P
L
R
K
A
N
L
Chimpanzee
Pan troglodytes
XP_001153533
746
85517
T59
G
G
L
F
Q
G
K
T
P
L
R
K
A
N
L
Rhesus Macaque
Macaca mulatta
XP_001109645
746
85683
T59
G
G
L
F
Q
G
K
T
P
L
R
K
A
N
L
Dog
Lupus familis
XP_850934
748
86144
T59
A
G
L
F
Q
D
K
T
P
L
R
K
P
N
P
Cat
Felis silvestris
Mouse
Mus musculus
NP_082385
745
85876
N59
G
E
P
F
Q
G
K
N
S
L
R
K
A
K
L
Rat
Rattus norvegicus
NP_001101260
744
85432
T59
G
E
P
F
Q
G
K
T
S
L
R
K
A
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516385
623
69684
I54
H
P
P
S
P
D
D
I
K
D
T
S
V
P
C
Chicken
Gallus gallus
NP_989768
739
85048
P58
N
S
P
A
F
S
K
P
A
L
I
L
S
S
V
Frog
Xenopus laevis
NP_001086751
715
81991
V60
N
A
E
Q
N
C
K
V
E
P
G
K
I
T
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798362
948
108486
D159
R
I
D
Q
P
V
Q
D
E
T
P
G
P
E
V
Poplar Tree
Populus trichocarpa
XP_002327911
811
91572
T79
G
R
S
F
K
V
E
T
L
C
D
F
S
Q
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
97.5
90.3
N.A.
79.2
79.1
N.A.
40.1
57.5
53.8
N.A.
N.A.
N.A.
N.A.
N.A.
31.6
Protein Similarity:
100
99.3
98.6
93.9
N.A.
87.6
87.4
N.A.
53
72.5
70
N.A.
N.A.
N.A.
N.A.
N.A.
49.4
P-Site Identity:
100
100
100
73.3
N.A.
66.6
73.3
N.A.
0
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
73.3
N.A.
66.6
73.3
N.A.
0
33.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
20.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
39.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
10
0
0
0
0
10
0
0
0
46
0
10
% A
% Cys:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
10
% C
% Asp:
0
0
10
0
0
19
10
10
0
10
10
0
0
0
0
% D
% Glu:
0
19
10
0
0
0
10
0
19
0
0
0
0
10
0
% E
% Phe:
0
0
0
64
10
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
55
37
0
0
0
46
0
0
0
0
10
10
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
10
0
0
10
0
10
0
0
% I
% Lys:
0
0
0
0
10
0
73
0
10
0
0
64
0
19
0
% K
% Leu:
0
0
37
0
0
0
0
0
10
64
0
10
0
0
46
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
19
0
0
0
10
0
0
10
0
0
0
0
0
37
0
% N
% Pro:
0
10
37
0
19
0
0
10
37
10
10
0
19
10
19
% P
% Gln:
0
0
0
19
55
0
10
0
0
0
0
0
0
10
0
% Q
% Arg:
10
10
0
0
0
0
0
0
0
0
55
0
0
0
0
% R
% Ser:
0
10
10
10
0
10
0
0
19
0
0
10
19
10
0
% S
% Thr:
0
0
0
0
0
0
0
55
0
10
10
0
0
10
0
% T
% Val:
0
0
0
0
0
19
0
10
0
0
0
0
10
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _